Training course on mixture toxicity in the frame of the STAR project
SCK•CEN
Boeretang 200
Mol
Overzicht
Contaminants never occur in isolation yet legislation is still largely based on effects of single compounds. In addition, more and more data are becoming available that suggest that compounds can exert effects in organisms when present in mixtures in concentration ranges at which the single contaminants do not induce effects. The examination of combined exposures, which corresponds much more realistically to exposure conditions in the environment than the analysis of single substances, entails major methodological difficulties in the experimentation and evaluation procedure. This workshop organised in the context of the European STAR project (Strategy Towards Allied Radioecology) intends to introduce you to some of the approaches and methodologies used in studying and predicting mixture toxicity effects.
The workshop will be a mixture of theoretical presentations and individual practical calculation sessions.
Onderwerpen
This workshop aims to provide:
- A description of the principal concepts of concentration addition and independent action for predicting mixture toxicity, their range of applicability and their limitations.
- An overview of the available designs for a particular mixture toxicity related research question.
- An overview of ways to address deviations from the existing reference models
- An in-depth knowledge on the concept of the Dynamic-Energy-Budget (DEB) theory, and the effects of toxicants and mixture exposure within this theory.
- Practical statistical approaches to be able to tackle linear and generalised linear modelling and to describe dose-effect relationships
- Concepts on environmental risk assessment approaches in an multiple contaminant context.
Doelpubliek
This workshop intends to attract Ph.D students and scientific researchers that are now confronted with the challenges of assessing or predicting biological effects in mixed exposures situations. As the general concepts discussed in this workshop apply to different fields of research, participants of all fields of (eco)toxicology are welcome.
Programma
Het volledige programma kan hier worden gedownload:
Training course of mixture toxicity in the frame of the STAR project.pdf
Prijs
Participation fee is 100 euro for all participants. This fee includes lunch (on Tuesday, Wednesday and Thursday), coffee breaks and handouts of the presentations, welcoming reception and walking dinner on Monday and course dinner on Wednesday.
Registratie
Registration deadline is January 17, 2014, please register using the registration button above.
Participation fee is 100 euro. This fee includes lunch, coffee breaks and handouts of the presentations, welcoming reception on Wednesday and walking dinner on Thursday.
Your registration is only final when you have made your payment by creditcard or bank transfer. You can use our E-terminal application (https://registrations.app.sckcen.be/E-terminal/PlaceOrder?mode=1) for paying by creditcard, or you can transfer the money to our bank account IBAN BE 58 5502 7124 0079 of SCK•CEN, Herrmann Debrouxlaan 40, B-1160 Brussels. The address of the bank is Dexia Bank, Koning Albert II laan 30b2, B-1000 Brussels (SWIFT BIC-code GKCCBEBB). Please make sure that the payment should be made net of all bank charges and commission. Please indicate "Academy course STAR" and your name on the bank transfer.